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Article

YTHDF2 promotes spermagonial adhesion through modulating MMPs decay via m6A/mRNA pathway.

Cell death & disease - 20 Jan 2020

Huang Tao, Liu Zidong, Zheng Yi, Feng Tongying, Gao Qiang, Zeng Wenxian

Abstract excerpt

As the foundation of male fertility, spermatogenesis is a complicated and highly controlled process. YTHDF2 plays regulatory roles in biological processes through accelerating the degradation of target mRNAs. However, the function of YTHDF2 in spermatogenesis remains elusive. Here, we knocked out Ythdf2 in mouse spermatogonia via CRISPR/Cas9, and found that depletion of Ythdf2 mainly downregulated the expression...

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Identifiers

PMID: 31959747
DOI: 10.1038/s41419-020-2235-4
PMCID: PMC6971064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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