Article
Molecular and Genomic Alterations in Glioblastoma Multiforme.
The American journal of pathology - 1 Jul 2015
Crespo Ines, Vital Ana Louisa, Gonzalez-Tablas María, Patino María del Carmen, Otero Alvaro, Lopes María Celeste, de Oliveira Catarina, Domingues Patricia, Orfao Alberto, Tabernero Maria Dolores
Abstract excerpt
In recent years, important advances have been achieved in the understanding of the molecular biology of glioblastoma multiforme (GBM); thus, complex genetic alterations and genomic profiles, which recurrently involve multiple signaling pathways, have been defined, leading to the first molecular/genetic classification of the disease. In this regard, different genetic alterations and genetic pathways appear to...
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