Article
Molecular characteristics and clinical features of multifocal glioblastoma.
Journal of neuro-oncology - 1 Jun 2020
Dono Antonio, Wang Emily, Lopez-Rivera Victor, Ramesh Arvind V, Tandon Nitin, Ballester Leomar Y, Esquenazi Yoshua
Abstract excerpt
INTRODUCTION: Glioblastomas (GBMs) usually occur as a solitary lesion; however, about 0.5-35% present with multiple lesions (M-GBM). The genetic landscape of GBMs have been thoroughly investigated; nevertheless, differences between M-GBM and single-foci GBM (S-GBM) remains unclear. The present study aimed to determine differences in clinical and molecular characteristics between M-GBM and S-GBM. METHODS: A...
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