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Article

Treatment of brain metastases in the modern genomic era.

Pharmacology & therapeutics - 1 Feb 2017

Dagogo-Jack Ibiayi, Gill Corey M, Cahill Daniel P, Santagata Sandro, Brastianos Priscilla K

Abstract excerpt

Development of brain metastasis (BM) portends a dismal prognosis for patients with cancer. Melanomas and carcinomas of the lung, breast, and kidney are the most common malignancies to metastasize to the brain. Recent advances in molecular genetics have enabled the identification of actionable, clinically relevant genetic alterations within primary tumors and their corresponding metastases. Adoption of...

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PMID: 27773784
DOI: 10.1016/j.pharmthera.2016.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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