Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Next generation sequencing unravels a gliosarcoma mimicking cerebral osteosarcoma.

Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia - 1 Jan 2025

Marti-Macia Clara, Navarro Lara, San-Miguel Teresa, Megias Javier, Carbonell-Zamorano Javier, Sanchez-Pardo Moisés, Roselló-Sastre Esther

Abstract excerpt

This study presents a case of a woman with recurrent headaches and nausea. Following initial surgery, the pathological diagnosis suggested primary cerebral osteosarcoma. However, despite osteosarcoma-directed chemotherapy, the patient experienced recurrence. A comprehensive diagnostic revision, including next generation sequencing, revealed mutations typical of glioblastoma. These findings highlight the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Diagnosis, Differential

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Mutation

Share to Neoplasm Recurrence, Local

Share to Osteosarcoma

Source

Identifiers

PMID: 40349619
DOI: 10.1016/j.patol.2025.100825

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Next generation sequencing unravels a gliosarcoma mimicking cerebral osteosarcoma.PMID 40349619Read ↗

Clinical Insights and Management Strategies for Gliosarcoma: A Case ReportSemantic proximity Read ↗

MOLECULAR PATHOLOGY OF MALIGNANT GLIOMASSemantic proximity Read ↗

Molecular Testing of Brain TumorSemantic proximity Read ↗

A Retrospective Genomic Landscape of 661 Young Adult Glioblastomas Diagnosed Using 2016 WHO Guidelines for Central Nervous System Tumors.Semantic proximity Read ↗

Next-generation sequencing reveals novel mutations in a collision tumor of glioblastoma and meningioma.Semantic proximity Read ↗

Gliosarcoma with Osteosarcomatous Component: A Case Report and Short Review IllustrationSemantic proximity Read ↗

Demographic, radiographic, molecular and clinical characteristics of primary gliosarcoma and differences to glioblastoma.Semantic proximity Read ↗

The Significance of BRAF Mutation in the Epithelioid Glioblastoma Subtype: A Systematic Literature Review and a Case Report with a Unique Intraventricular Topography.Semantic proximity Read ↗

Genomic landscape of gliosarcoma: distinguishing features and targetable alterations.Semantic proximity Read ↗

Molecular biology of glioblastoma: Classification and mutational locations.Semantic proximity Read ↗

Primary and secondary gliosarcomas: clinical, molecular and survival characteristics.Semantic proximity Read ↗

Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.