Low levels of HIV-1 drug resistance mutations in patients who achieved viral re-suppression without regimen switch: a retrospective study.

doi:10.1186/s12866-020-1706-1

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Article

Low levels of HIV-1 drug resistance mutations in patients who achieved viral re-suppression without regimen switch: a retrospective study.

BMC microbiology - 20 Jan 2020

Onwuamah Chika K, Okpokwu Jonathan, Audu Rosemary, Imade Godwin, Meloni Seema T, Okwuraiwe Azuka, Chebu Philippe, Musa Adesola Z, Chaplin Beth, Dalhatu Ibrahim, Agbaji Oche, Samuels Jay, Ezechi Oliver, Ahmed Mukhtar, Odaibo Georgina, Olaleye David O, Okonkwo Prosper, Salako Babatunde Lawal, Raizes Elliot, Yang Chunfu, Kanki Phyllis J, Idigbe Emmanuel O

Abstract excerpt

BACKGROUND: We identified a HIV-positive cohort in virologic failure (VF) who re-suppressed without drug switch. We characterized their drug resistance mutations (DRM) and adherence profiles to learn how to better manage HIV drug resistance. A retrospective cohort study utilizing clinical data and stored samples. Patients received ART at three Nigerian treatment centres. Plasma samples stored when they were in VF...

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PMID: 31959116
DOI: 10.1186/s12866-020-1706-1
PMCID: PMC6971913

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