Pretreatment HIV drug resistance increases regimen switches in sub-Saharan Africa.

doi:10.1093/cid/civ656

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Article

Pretreatment HIV drug resistance increases regimen switches in sub-Saharan Africa.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Dec 2015

Boender T Sonia, Hoenderboom Bernice M, Sigaloff Kim C E, Hamers Raph L, Wellington Maureen, Shamu Tinei, Siwale Margaret, Labib Maksimos Eman E F, Nankya Immaculate, Kityo Cissy M, Adeyemo Titilope A, Akanmu Alani Sulaimon, Mandaliya Kishor, Botes Mariette E, Ondoa Pascale, Rinke de Wit Tobias F

Abstract excerpt

BACKGROUND: After the scale-up of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection in Africa, increasing numbers of patients have pretreatment drug resistance. METHODS: In a large multicountry cohort of patients starting standard first-line ART in six African countries, pol genotyping was retrospectively performed if viral load (VL) ≥1000 cps/mL. Pretreatment drug resistance was...

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PMID: 26240203
DOI: 10.1093/cid/civ656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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