Article
High Prevalence of Drug Resistance Mutations Among Patients Failing First-Line Antiretroviral Therapy and Predictors of Virological Response 24 Weeks After Switch to Second-Line Therapy in São Paulo State, Brazil.
AIDS research and human retroviruses - 1 Feb 2018
Matsuda Elaine Monteiro, Coelho Luana Portes Ozório, Romero Giselle de Faria, de Moraes Monica Jacques, Lopez-Lopes Giselle Ibete Silva, Morejon Karen, Campeas Alexandre Ely, Cabral Gabriela Bastos, Brígido Luís Fernando de Macedo
Abstract excerpt
Universal antiretroviral treatment with sustained viral suppression benefits patients and reduces HIV transmission. Effectiveness of therapy may be limited by antiretroviral drug resistance. Information on the resistance profile at treatment failure and its impact on antiretroviral drugs may subsidize subsequent treatment strategies. Partial pol sequences from 319 patients failing first-line therapy were analyzed...
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