Article
Current management challenges in HIV: antiretroviral resistance.
The AIDS reader - 1 Mar 2003
Kuritzkes Daniel R, Boyle Brian A, Gallant Joel E, Squires Kathleen E, Zolopa Andrew
Abstract excerpt
Emergence of drug-resistant viral variants is a major reason why HIV-infected patients experience viral rebound during antiretroviral therapy. Although combination antiretroviral therapy substantially inhibits viral replication, replication-competent mutant virus remains. In addition, it is now clear that virologic failure is not necessarily caused by failure of all drugs in a regimen. The use of...
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