Article
Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria.
PloS one - 1 Jan 2013
Rawizza Holly E, Chaplin Beth, Meloni Seema T, Darin Kristin M, Olaitan Oluremi, Scarsi Kimberly K, Onwuamah Chika K, Audu Rosemary A, Chebu Philippe R, Imade Godwin E, Okonkwo Prosper, Kanki Phyllis J
Abstract excerpt
BACKGROUND: To date, antiretroviral therapy (ART) guidelines and programs in resource-limited settings (RLS) have focused on 1(st)- and 2(nd)-line (2 L) therapy. As programs approach a decade of implementation, policy regarding access to 3(rd)-line (3 L) ART is needed. We aimed to examine the impact of maintaining patients on failing 2 L ART on the accumulation of protease (PR) mutations. METHODS AND FINDINGS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.