Article
HIV drug resistance mutations among patients failing second-line antiretroviral therapy in Rwanda.
Antiviral therapy - 1 Jan 2016
Ndahimana Jean d'Amour, Riedel David J, Muhayimpundu Ribakare, Nsanzimana Sabin, Niyibizi Gad, Mutaganzwa Emmanuel, Mulindabigwi Augustin, Baribwira Cyprien, Kiromera Athanase, Jagodzinski Linda L, Peel Sheila A, Redfield Robert R
Abstract excerpt
BACKGROUND: Studies of patients failing second-line antiretroviral therapy (ART) in resource-limited settings (RLS) are few. Evidence suggests most patients who appear to be virologically failing do so not due to drug resistance but to poor adherence, which, if properly addressed, could allow continued use of less expensive first- and second-line regimens. Drug resistant mutations (DRMs) were characterized among...
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