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The somatic mutation landscape of Chinese Colorectal Cancer

13 Dec 2019

Abstract excerpt

Colorectal cancer (CRC) is the fifth leading cause of cancer-related death in China. The incidence of Chinese CRC has increased dramatically with the changes of dietary and lifestyle. However, the genetic landscape of Chinese colorectal cancer mutation is still poorly understood. In this study, we have performed whole exome-sequencing analysis of 63 CRC cases. We found that Chinese CRC were hypermutated, which...

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PMID: 31956350
DOI: 10.7150/jca.37017

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