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Article

Molecular Profiling Provides Clinical Insights Into Targeted and Immunotherapies as Well as Colorectal Cancer Prognosis.

Gastroenterology - 1 Aug 2023

Guo Linwei, Wang Yunjin, Yang Wenxiao, Wang Chenchen, Guo Tian'an, Yang Jingcheng, Shao Zhiming, Cai Guoxiang, Cai Sanjun, Zhang Liying, Hu Xin, Xu Ye

Abstract excerpt

BACKGROUND & AIMS: Tumor genetic testing is indispensable in the management of primary and metastatic colorectal cancer (CRC), yet the indications for genomics-guided precision medicine and immunotherapy must be better understood and defined. METHODS: We prospectively sequenced tumors from 869 Chinese patients with CRC by a large panel and evaluated the clinical significance of single-gene somatic mutations and...

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PMID: 37146911
DOI: 10.1053/j.gastro.2023.04.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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