Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of genomic alterations in Chinese colorectal cancer patients with liver metastases.

Journal of translational medicine - 19 Jul 2021

Wang Hong-Wei, Yan Xiao-Luan, Wang Li-Jun, Zhang Meng-Huan, Yang Chun-He, Wei-Liu, Jin Ke-Min, Bao Quan, Li Juan, Wang Kun, Xing Bao-Cai

Abstract excerpt

BACKGROUND: The exploration of genomic alterations in Chinese colorectal liver metastasis (CRLM) is limited, and corresponding genetic biomarkers for patient's perioperative management are still lacking. This study aims to understand genome diversification and complexity that developed in CRLM. METHODS: A custom-designed IDT capture panel including 620 genes was performed in the Chinese CRLM cohort, which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to China
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Filaggrin Proteins

Share to Genomics

Share to Liver Neoplasms

Share to Mutation

Share to Phosphatidylinositol 3-Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 34281583
DOI: 10.1186/s12967-021-02986-0
PMCID: PMC8287676

Genes

APC
FLG
KRAS
SMAD4
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of genomic alterations in Chinese colorectal cancer patients with liver metastases.PMID 34281583Read ↗

Characterization of Genomic Alterations in Colorectal Liver Metastasis and Their Prognostic ValueSemantic proximity Read ↗

Integrative genomic analysis identifies clinically relevant prognostic markers for colorectal cancer patients with liver metastasis.Semantic proximity Read ↗

Comparative Genomic Analysis of Primary and Synchronous Metastatic Colorectal CancersSemantic proximity Read ↗

Comprehensive Mutation Profiling of Colorectal Cancer Patients With Lung or Liver Metastasis by Targeted Next-Generation Sequencing.Semantic proximity Read ↗

High Concordance of Genomic Profiles between Primary and Metastatic Colorectal Cancer.Semantic proximity Read ↗

Genomic profiles of colorectal carcinoma with liver metastases and newly identified fusion genesSemantic proximity Read ↗

Colorectal Cancer Genetic Heterogeneity Delineated by Multi-Region Sequencing.Semantic proximity Read ↗

Genomic Alterations and Clinical Characterization in Chinese Patients with Metastatic Colorectal Cancer.Semantic proximity Read ↗

Mutational profile evaluates metastatic capacity of Chinese colorectal cancer patients, revealed by whole-exome sequencing.Semantic proximity Read ↗

Molecular dissection of CRC primary tumors and their matched liver metastases reveals critical role of immune microenvironment, EMT and angiogenesis in cancer metastasis.Semantic proximity Read ↗

The somatic mutation landscape of Chinese Colorectal CancerSemantic proximity Read ↗

The mutational factors influencing the therapeutic response and prognosis of stage IV CRC patients undergoing simultaneous resection of primary and liver metastatic lesions and subsequent adjuvant therapy---A pilot study on the prognosis of stage IV CRC.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.