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Article

SOX9 promotes tumor progression through the axis BMI1-p21CIP

15 Jan 2020

Abstract excerpt

Abstract The developmental regulator SOX9 is linked to cancer progression mainly as a result of its role in the regulation of cancer stem cells (CSCs). However, its activity in the differentiated cells that constitute the heterogeneous tumor bulk has not been extensively studied. In this work, we addressed this aspect in gastric cancer, glioblastoma and pancreatic adenocarcinoma. SOX9 silencing studies revealed...

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PMID: 31941916
DOI: 10.1038/s41598-019-57047-w

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