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Article

SOX9 Elevation Acts with Canonical WNT Signaling to Drive Gastric Cancer Progression

28 Aug 2016

Abstract excerpt

Gastric cancer remains one of the leading causes of global cancer mortality due to therapy resistance, with Helicobacter pylori (H. pylori) infection being a major risk factor. In this study, we report the significance of an elevation of the stem cell regulator SOX9 in bacteria-infected human gastritis and cancer samples, paralleling increased levels of TNFα SOX9 elevation was more intense in specimens containing...

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PMID: 27569216
DOI: 10.1158/0008-5472.can-16-1120

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