Article
MHC Class II (DRB) Promoter Polymorphism and Its Role in Parasite Control among Malaria Patients.
Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2020
Sar Pranati, Agarwal Aarushi, Vadodariya Devansi Hansrajbhai, Kariya Hiral, Khuman Jaydipbhai, Dalai Sarat
Abstract excerpt
MHC class II (MHCII) molecules are cell surface glycoproteins that play an important role to develop adaptive immune responses. MHCII-disease association is not restricted to structural variation alone but also may extend to genetic variations, which may modulate gene expression. The observed variations in class II gene expression make it possible that the association of MHCII polymorphism with diseases may...
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