HLA-DR Class II expression on myeloid and lymphoid cells in relation to HLA-DRB1 as a genetic risk factor for visceral leishmaniasis.

doi:10.1111/imm.13018

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

HLA-DR Class II expression on myeloid and lymphoid cells in relation to HLA-DRB1 as a genetic risk factor for visceral leishmaniasis.

Immunology - 1 Feb 2019

Singh Bhawana, Fakiola Michaela, Sudarshan Medhavi, Oommen Joyce, Singh Siddharth Sankar, Sundar Shyam, Blackwell Jenefer M

Abstract excerpt

Genetic variation at HLA-DRB1 is a risk factor for visceral leishmaniasis (VL) caused by Leishmania donovani. The single nucleotide polymorphism rs9271252 upstream of the DRB1 gene provides a perfect tag for protective versus risk HLA-DRB1 four-digit alleles. In addition to the traditional role of the membrane-distal region of HLA class II molecules in antigen presentation and CD4 T-cell activation, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to HLA-DRB1 Chains

Share to Homozygote

Share to Infant

Share to Leishmaniasis, Visceral

Share to Lymphocytes

Share to Myeloid Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 30403401
DOI: 10.1111/imm.13018
PMCID: PMC6328996

Genes

CD4
CD19
CD14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-DR Class II expression on myeloid and lymphoid cells in relation to HLA-DRB1 as a genetic risk factor for visceral leishmaniasis.PMID 30403401Read ↗

Epitope-Binding Characteristics for Risk versus Protective DRB1 Alleles for Visceral Leishmaniasis.Semantic proximity Read ↗

Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis.Semantic proximity Read ↗

Human genetics of leishmania infections.Semantic proximity Read ↗

MHC Class II (DRB) Promoter Polymorphism and Its Role in Parasite Control among Malaria Patients.Semantic proximity Read ↗

Genetic and functional evaluation of the role of DLL1 in susceptibility to visceral leishmaniasis in India.Semantic proximity Read ↗

Predicted epitope binding core motifs and common amino acid polymorphisms distinguish protective- from susceptibility-associated HLA alleles in leishmaniasisSemantic proximity Read ↗

HLA Alleles B*53:01 and C*06:02 Are Associated With Higher Risk of P. falciparum Parasitemia in a Cohort in Uganda.Semantic proximity Read ↗

Inhibitory KIR ligands are associated with higher<i>P. falciparum</i>parasite prevalenceSemantic proximity Read ↗

Follicular lymphoma-protective HLA class II variants correlate with increased HLA-DQB1 protein expression.Semantic proximity Read ↗

Association of Inhibitory Killer Cell Immunoglobulin-like Receptor Ligands With Higher Plasmodium falciparum Parasite Prevalence.Semantic proximity Read ↗

Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria.Semantic proximity Read ↗

HLA-DRB1*04 and DRB1*10 are associated with resistance and susceptibility, respectively, in Brazilian and Vietnamese leprosy patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.