Article
TERT-rs33963617 and CLPTM1L-rs77518573 reduce the risk of non-small cell lung cancer in Chinese population.
Gene - 20 Mar 2020
Ji Zhi, Li Ying, Xiang Cheng, Luo Xia, Yuan Peihong, Long Jieyi, Shen Na, Shen Ying, Deng Lingyan, Li Jiaoyuan, Cheng Liming
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) have identified 5p15.33 as a susceptible locus for lung cancer. However, for non-small cell lung cancer (NSCLC), low-frequency risk variants in this region have not been systematically studied. We intended to explore the associations between low-frequency variants on 5p15.33 and NSCLC using a next-generation sequencing based approach in this study. METHODS: We...
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