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Genetic variations in TERT-CLPTM1L locus are associated with risk of lung cancer in Chinese population.

Molecular carcinogenesis - 1 Nov 2013

Zhong Rong, Liu Li, Zou Li, Zhu Yaowu, Chen Wei, Zhu Beibei, Shen Na, Rui Rui, Long Lu, Ke Juntao, Lu Xuzai, Zhang Ti, Zhang Yu, Wang Zhenling, Liu Lifeng, Sun Yu, Cheng Liming, Miao Xiaoping

Abstract excerpt

Recent genome-wide association studies (GWAS) have reported multiple genetic variations at 5p15.33 (TERT-CLPTM1L) associated with risk of lung cancer. However, most of the associated variations identified by GWAS thus far are unlikely to be the actual causal variants, but may be mostly marker-single nucleotide polymorphisms tagging functional variations that influence gene expression. This study aimed to explore...

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PMID: 23908149
DOI: 10.1002/mc.22043

Genes

TERT

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