Replication study in Chinese population and meta-analysis supports association of the 5p15.33 locus with lung cancer.

doi:10.1371/journal.pone.0062485

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Replication study in Chinese population and meta-analysis supports association of the 5p15.33 locus with lung cancer.

PloS one - 1 Jan 2013

Ke Juntao, Zhong Rong, Zhang Ti, Liu Lifeng, Rui Rui, Shen Na, Sun Yu, Liu Li, Cheng Liming, Miao Xiao-Ping

Abstract excerpt

BACKGROUND: Common genetic polymorphisms on chromosome 5p15.33, including rs401681 in cleft lip and palate transmembrane 1-like gene (CLPTM1L), have been implicated in susceptibility to lung cancer through genome-wide association studies (GWAS); however, subsequent replication studies yielded controversial results. METHODOLOGY AND FINDINGS: A hospital-based case-control study in a Chinese population was conducted...

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PMID: 23653681
DOI: 10.1371/journal.pone.0062485
PMCID: PMC3641186

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