Article
Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population.
Carcinogenesis - 1 Jun 2009
Jin Guangfu, Xu Lin, Shu Yongqian, Tian Tian, Liang Jie, Xu Yan, Wang Furu, Chen Jianjian, Dai Juncheng, Hu Zhibin, Shen Hongbing
Abstract excerpt
Chromosome 5p15.33, containing TERT and CLPTM1L genes, was recently identified as one of the susceptible regions for lung cancer in Caucasian populations. We hypothesized that single-nucleotide polymorphisms (SNPs) identified in this region in Caucasians are also important in the development of lung cancer in Chinese population. To test this hypothesis, we genotyped two most significant SNPs reported in...
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