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Article

Fine mapping of chromosome 5p15.33 identifies novel lung cancer susceptibility loci in Han Chinese.

International journal of cancer - 1 Aug 2017

Dong Jing, Cheng Yang, Zhu Meng, Wen Yang, Wang Cheng, Wang Yuzhuo, Geng Liguo, Shen Wei, Liu Jia, Li Zhihua, Zhang Jiahui, Ma Hongxia, Dai Juncheng, Jin Guangfu, Hu Zhibin, Shen Hongbing

Abstract excerpt

Genome-wide association studies in European and Asian populations have consistently identified chromosome 5p15.33 as a lung cancer susceptibility region. To investigate further the genetic architecture of common variants in this region, we conducted a two-stage fine-mapping analysis discovered by targeted resequencing of 200 cases and 300 controls individually, and validated in multiethnic lung cancer Genome wide...

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PMID: 28335076
DOI: 10.1002/ijc.30702

Genes

TERT
TPPP

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