Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk.

Carcinogenesis - 1 Oct 2011

Pande Mala, Spitz Margaret R, Wu Xifeng, Gorlov Ivan P, Chen Wei V, Amos Christopher I

Abstract excerpt

Chromosome 5p15.33 has been identified by genome-wide association studies as one of the regions that associate with lung cancer risk. A few single-nucleotide polymorphisms (SNPs) in the telomerase reverse transcriptase (TERT) and cleft lip and palate transmembrane 1-like (CLPTM1L) genes located in this region have shown consistent associations. We performed dense genotyping of SNPs in this region to refine the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Carcinoma, Squamous Cell
Share to Chromosomes, Human, Pair 5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Proteins

Share to Odds Ratio

Share to Small Cell Lung Carcinoma

Share to Smoking

Share to Telomerase

Source

Open in PubMed Open full text

Identifiers

PMID: 21771723
DOI: 10.1093/carcin/bgr136
PMCID: PMC3179422

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk.PMID 21771723Read ↗

Lung cancer susceptibility locus at 5p15.33.Semantic proximity Read ↗

Fine mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci.Semantic proximity Read ↗

Significant association of 5p15.33 (TERT-CLPTM1L genes) with lung cancer in Chinese Han population.Semantic proximity Read ↗

Study of genetic variants in chromosome 5p15.33 region in non-smoker lung cancer patients.Semantic proximity Read ↗

The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia.Semantic proximity Read ↗

Common 5p15.33 and 6p21.33 variants influence lung cancer risk.Semantic proximity Read ↗

Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers.Semantic proximity Read ↗

Systematic Review of Genetic Variation in Chromosome 5p15.33 and Telomere Length as Predictive and Prognostic Biomarkers for Lung Cancer.Semantic proximity Read ↗

Fine mapping of chromosome 5p15.33 identifies novel lung cancer susceptibility loci in Han Chinese.Semantic proximity Read ↗

Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population.Semantic proximity Read ↗

TERT-rs33963617 and CLPTM1L-rs77518573 reduce the risk of non-small cell lung cancer in Chinese population.Semantic proximity Read ↗

Multiple variants of TERT and CLPTM1L constitute risk factors for lung adenocarcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.