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Article

The MBOAT7 rs641738 variant is associated with an improved outcome in primary sclerosing cholangitis.

Clinics and research in hepatology and gastroenterology - 1 Oct 2020

Freund Cora, Wahlers Arne, Begli Nima Haji, Leopold Yvonne, Klöters-Plachky Petra, Mehrabi Arianeb, Mohr Isabelle, Sander Julia, Rupp Christian, Gotthardt Daniel Nils, Weiss Karl Heinz

Abstract excerpt

BACKGROUND AND AIMS: Primary sclerosing cholangitis (PSC) is a chronic cholestatic disease that causes liver cirrhosis, leading to liver failure. Additionally, PSC is a risk factor for cholangiocarcinoma. Its mechanism is unknown, and liver transplantation remains the sole curative option. The membrane bound O-acyltransferase domain containing 7 (MBOAT7) rs641738 and rs626283 variant alleles have been associated...

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Identifiers

PMID: 31928970
DOI: 10.1016/j.clinre.2019.12.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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