Article
Primary sclerosing cholangitis.
Best practice & research. Clinical gastroenterology - 1 Oct 2010
Karlsen Tom H, Schrumpf Erik, Boberg Kirsten Muri
Abstract excerpt
Primary sclerosing cholangitis (PSC) is a chronic bile duct disease leading to fibrotic biliary strictures and liver cirrhosis. The patient population is heterogeneous with regard to disease progression and the presence of co-morbidities, complicating the practical handling of patients as well as studies of pathogenetic mechanisms. The aetiology of PSC is unknown, but the recent findings of several robust...
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