Article
Primary sclerosing cholangitis.
Best practice & research. Clinical gastroenterology - 1 Oct 2010
Karlsen Tom H, Schrumpf Erik, Boberg Kirsten Muri
Abstract excerpt
Primary sclerosing cholangitis (PSC) is a chronic bile duct disease leading to fibrotic biliary strictures and liver cirrhosis. The patient population is heterogeneous with regard to disease progression and the presence of co-morbidities, complicating the practical handling of patients as well as studies of pathogenetic mechanisms. The aetiology of PSC is unknown, but the recent findings of several robust...
Topics
- Bile Duct Neoplasms
- Bile Ducts, Intrahepatic
- Cholangiocarcinoma
- Cholangiography
- Cholangitis, Sclerosing
- Comorbidity
- Disease Progression
- Gallbladder Neoplasms
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
