Article
Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management.
Gastroenterology - 1 Sept 2013
Eaton John E, Talwalkar Jayant A, Lazaridis Konstantinos N, Gores Gregory J, Lindor Keith D
Abstract excerpt
Primary sclerosing cholangitis (PSC), first described in the mid-1850s, is a complex liver disease that is heterogeneous in its presentation. PSC is characterized by chronic cholestasis associated with chronic inflammation of the biliary epithelium, resulting in multifocal bile duct strictures that can affect the entire biliary tree. Chronic inflammation leads to fibrosis involving the hepatic parenchyma and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.