Article
Primary sclerosing cholangitis - a comprehensive review.
Journal of hepatology - 1 Dec 2017
Karlsen Tom H, Folseraas Trine, Thorburn Douglas, Vesterhus Mette
Abstract excerpt
Primary sclerosing cholangitis (PSC) is a rare disorder characterised by multi-focal bile duct strictures and progressive liver disease. Inflammatory bowel disease is usually present and there is a high risk of cholangiocarcinoma and colorectal cancer. Most patients ultimately require liver transplantation, after which disease recurrence may occur. With limited therapeutic options and a lack of proven...
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