The membrane-bound O-acyltransferase domain-containing 7 variant rs641738 increases inflammation and fibrosis in chronic hepatitis B.

doi:10.1002/hep.29064

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Article

The membrane-bound O-acyltransferase domain-containing 7 variant rs641738 increases inflammation and fibrosis in chronic hepatitis B.

Hepatology (Baltimore, Md.) - 1 Jun 2017

Thabet Khaled, Chan Henry Lik Yuen, Petta Salvatore, Mangia Alessandra, Berg Thomas, Boonstra Andre, Brouwer Willem P, Abate Maria Lorena, Wong Vincent Wai-Sun, Nazmy Maiiada, Fischer Janett, Liddle Christopher, George Jacob, Eslam Mohammed

Abstract excerpt

Chronic hepatitis B (CHB) is characterized by hepatic inflammation that promotes progression to cirrhosis and predisposes to the development of hepatocellular carcinoma (HCC). Subtle interindividual genetic variation as well as viral and environmental factors interact to determine disease progression between individuals. Recently, the rs641738 membrane-bound O-acyltransferase domain-containing 7 (MBOAT7)...

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PMID: 28109005
DOI: 10.1002/hep.29064

Genes

MBOAT7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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