Article
Value of pyrazinamide for composition of new treatment regimens for multidrug-resistant Mycobacterium tuberculosis in China.
BMC infectious diseases - 7 Jan 2020
Xia Hui, van den Hof Susan, Cobelens Frank, Zhou Yang, Zhao Bing, Wang Shengfen, Zhao Yanlin
Abstract excerpt
BACKGROUND: Pyrazinamide still may be a useful drug for treatment of rifampin-resistant (RR-TB) or multidrug-resistant tuberculosis (MDR-TB) in China while awaiting scale up of new drugs and regimens including bedaquiline and linezolid. The level of pyrazinamide resistance among MDR-TB patients in China is not well established. Therefore, we assessed pyrazinamide resistance in a representative sample and explored...
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