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Prevalence and transmission of pyrazinamide resistant Mycobacterium tuberculosis in China.

Tuberculosis (Edinburgh, Scotland) - 1 May 2016

Xu Peng, Wu Jie, Yang Chongguang, Luo Tao, Shen Xin, Zhang Yangyi, Nsofor Chijioke A, Zhu Guofeng, Gicquel Brigitte, Gao Qian

Abstract excerpt

Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug, however, there are relatively few available data on PZA resistant (PZA-R) rate in China. From June 2009 to June 2012, we selected 493 isolates from five field settings in China to investigate PZA-R by pncA gene sequencing. The result showed that PZA-R rate was 1.0% (2/196) among pan-susceptible isolates, 3.1% (4/130) among isoniazid (INH)...

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Identifiers

PMID: 27156619
DOI: 10.1016/j.tube.2016.02.008
PMCID: PMC5647815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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