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Characteristics of pncA mutations in multidrug-resistant tuberculosis in Taiwan

12 Sept 2011

Abstract excerpt

BACKGROUND: Pyrazinamide (PZA) is an important first-line drug in multidrug-resistant tuberculosis (MDRTB) treatment. However, the unreliable results obtained from traditional susceptibility testing limits its usefulness in clinical settings. The detection of pncA gene mutations is a potential surrogate of PZA susceptibility testing, especially in MDRTB isolates. The impact of genotypes of M. tuberculosis in pncA...

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Infectious Diseases and Tuberculosis
Pneumocystis jirovecii pneumonia detection and treatment
Tuberculosis Research and Epidemiology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21910892
DOI: 10.1186/1471-2334-11-240

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