Article
Multicenter Study of the Emergence and Genetic Characteristics of Pyrazinamide-Resistant Tuberculosis in China.
Antimicrobial agents and chemotherapy - 1 Sept 2016
Li Dange, Hu Yi, Werngren Jim, Mansjö Mikael, Zheng Xubin, Drobniewski Francis, Hoffner Sven, Xu Biao
Abstract excerpt
The aim of this study was to investigate the epidemiology of pyrazinamide (PZA) resistance and the associated risk factors as well as to evaluate the pncA gene loci as a marker for PZA resistance in China. A population-based multicenter study of pulmonary tuberculosis (TB) cases was carried out from 2011 to 2013 in four Chinese districts/counties with different geographic and socioeconomic features. Testing for...
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