Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations found in the pncA gene of Mycobacterium tuberculosis in clinical pyrazinamide-resistant isolates from a local region of China.

The Journal of international medical research - 1 Jan 2000

Zhang H, Bi L-J, Li C-Y, Sun Z-G, Deng J-Y, Zhang Xian-En

Abstract excerpt

This study was designed to investigate the presence of mutations in the pncA gene, minimum inhibitory concentrations and pyrazinamidase activity of pyrazinamide-resistant Mycobacterium tuberculosis. In total, 47 M. tuberculosis clinical isolates from a local region of China were assayed. Pyrazinamidase activity was measured by pyrazinamide deamination to pyrazinoic acid and ammonia, and a 721 bp region, including...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amidohydrolases
Share to Antitubercular Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Bacterial

Share to Drug Resistance, Microbial

Share to Microbial Sensitivity Tests

Share to Mycobacterium tuberculosis

Share to Pyrazinamide

Share to Tuberculosis

Source

Identifiers

PMID: 19930847
DOI: 10.1177/147323000903700517

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations found in the pncA gene of Mycobacterium tuberculosis in clinical pyrazinamide-resistant isolates from a local region of China.PMID 19930847Read ↗

Characterization of pncA Mutations and Prediction of PZA Resistance in Mycobacterium tuberculosis Clinical Isolates From Chongqing, ChinaSemantic proximity Read ↗

Pyrazinamide Resistance and pncA Mutation Profiles in Multidrug Resistant Mycobacterium TuberculosisSemantic proximity Read ↗

pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis clinical isolates from the southeast region of BrazilSemantic proximity Read ↗

Genetic and phenotypic characterization of pyrazinamide-resistant mycobacterium tuberculosis complex isolates in Japan.Semantic proximity Read ↗

Characterization of pncA mutations of pyrazinamide-resistant Mycobacterium tuberculosis in Korea.Semantic proximity Read ↗

Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis in Brazil.Semantic proximity Read ↗

Characterization of new mutations in pyrazinamide-resistant strains of Mycobacterium tuberculosis and identification of conserved regions important for the catalytic activity of the pyrazinamidase PncA.Semantic proximity Read ↗

Multicenter Study of the Emergence and Genetic Characteristics of Pyrazinamide-Resistant Tuberculosis in China.Semantic proximity Read ↗

Characterization of pncA mutations of pyrazinamide-resistant Mycobacterium tuberculosis in Turkey.Semantic proximity Read ↗

Relationship between pyrazinamide resistance, loss of pyrazinamidase activity, and mutations in the pncA locus in multidrug-resistant clinical isolates of Mycobacterium tuberculosis.Semantic proximity Read ↗

Mutations Associated with Pyrazinamide Resistance in Mycobacterium tuberculosis: A Review and Update.Semantic proximity Read ↗

pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates in Portugal.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.