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Article

miR-199 plays both positive and negative regulatory roles in Xenopus eye development.

Genesis (New York, N.Y. : 2000) - 1 Mar 2020

Ritter Ruth A, Ulrich Christina H, Brzezinska Bogna N, Shah Vrutant V, Zamora Melissa J, Kelly Lisa E, El-Hodiri Heithem M, Sater Amy K

Abstract excerpt

To investigate microRNA (miR) functions in early eye development, we asked whether eye field transcription factors (EFTFs) are targets of miR-dependent regulation in Xenopus embryos. Argonaute (AGO) ribonucleoprotein complexes, including miRs and targeted mRNAs, were coimmunoprecipitated from transgenic embryos expressing myc-tagged AGO under the control of the rax1 promoter; mRNAs for all EFTFs...

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PMID: 31909537
DOI: 10.1002/dvg.23354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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