Article
Patterning the optic neuroepithelium by FGF signaling and Ras activation.
Development (Cambridge, England) - 1 Dec 2001
Zhao S, Hung F C, Colvin J S, White A, Dai W, Lovicu F J, Ornitz D M, Overbeek P A
Abstract excerpt
During vertebrate embryogenesis, the neuroectoderm differentiates into neural tissues and also into non-neural tissues such as the choroid plexus in the brain and the retinal pigment epithelium in the eye. The molecular mechanisms that pattern neural and non-neural tissues within the neuroectoderm remain unknown. We report that FGF9 is normally expressed in the distal region of the optic vesicle that is destined...
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