Article
MicroRNAs and ectodermal specification I. Identification of miRs and miR-targeted mRNAs in early anterior neural and epidermal ectoderm.
Developmental biology - 15 Jun 2017
Shah Vrutant V, Soibam Benjamin, Ritter Ruth A, Benham Ashley, Oomen Jamina, Sater Amy K
Abstract excerpt
The establishment of cell lineages occurs via a dynamic progression of gene regulatory networks (GRNs) that underlie developmental commitment and differentiation. To investigate how microRNAs (miRs) function in this process, we compared miRs and miR targets at the initiation of the two major ectodermal lineages in Xenopus. We used next-generation sequencing to identify over 170 miRs expressed in midgastrula...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.