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Article

Regulation of vertebrate eye development by Rx genes.

The International journal of developmental biology - 1 Jan 2004

Bailey Travis J, El-Hodiri Heithem, Zhang Li, Shah Rina, Mathers Peter H, Jamrich Milan

Abstract excerpt

The paired-like homeobox-containing gene Rx has a critical role in the eye development of several vertebrate species including Xenopus, mouse, chicken, medaka, zebrafish and human. Rx is initially expressed in the anterior neural region of developing embryos, and later in the retina and ventral hypothalamus. Abnormal regulation or function of Rx results in severe abnormalities of eye formation. Overexpression of...

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Identifiers

PMID: 15558469
DOI: 10.1387/ijdb.041878tb

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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