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Article

Argonaute2 suppresses Drosophila fragile X expression preventing neurogenesis and oogenesis defects.

PloS one - 27 Oct 2009

Pepper Anita S-R, Beerman Rebecca W, Bhogal Balpreet, Jongens Thomas A

Abstract excerpt

Fragile X Syndrome is caused by the silencing of the Fragile X Mental Retardation gene (FMR1). Regulating dosage of FMR1 levels is critical for proper development and function of the nervous system and germ line, but the pathways responsible for maintaining normal expression levels are less clearly defined. Loss of Drosophila Fragile X protein (dFMR1) causes several behavioral and developmental defects in the...

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Source

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Identifiers

PMID: 19888420
DOI: 10.1371/journal.pone.0007618
PMCID: PMC2770736

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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