Article
Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character.
Developmental biology - 15 Nov 2014
Fish Margaret B, Nakayama Takuya, Fisher Marilyn, Hirsch Nicolas, Cox Amanda, Reeder Rollin, Carruthers Samantha, Hall Amanda, Stemple Derek L, Grainger Robert M
Abstract excerpt
The retinal anterior homeobox (rax) gene encodes a transcription factor necessary for vertebrate eye development. rax transcription is initiated at the end of gastrulation in Xenopus, and is a key part of the regulatory network specifying anterior neural plate and retina. We describe here a Xenopus tropicalis rax mutant, the first mutant analyzed in detail from a reverse genetic screen. As in other vertebrates,...
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