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Article

A functional variant in CHK1 contributes to increased risk of nasopharyngeal carcinoma in a Han Chinese population.

Journal of cellular biochemistry - 1 Jun 2020

Guo Zhen, Wang Youhong, Zhao Yu, Jin Yi, An Liang, Xu Heng, Liu Zhaoqian, Chen Xiaoping, Zhou Honghao, Wang Hui, Zhang Wei

Abstract excerpt

DNA damage checkpoints act as a supervisor by preventing the course of cell cycle upon DNA damage and keeping the steadiness of genome. Checkpoint kinase 1 (CHK1) cannot be ignore in the etiology of numerous human cancers including nasopharyngeal cancer (NPC). To discuss genetic polymorphisms of CHK1 rs492510 in the occurrence of NPC was our objective. Rs492510 polymorphism of CHK1 was genotyped in 684 patients...

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Identifiers

PMID: 31904144
DOI: 10.1002/jcb.29592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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