Article
An extended genome-wide association study identifies novel susceptibility loci for nasopharyngeal carcinoma.
Human molecular genetics - 15 Aug 2016
Cui Qian, Feng Qi-Sheng, Mo Hao-Yuan, Sun Jian, Xia Yun-Fei, Zhang Hongxing, Foo Jia Nee, Guo Yun-Miao, Chen Li-Zhen, Li Ming, Liu Wen-Sheng, Xu Miao, Zhou Gangqiao, He Fuchu, Yu Xueqing, Jia Wei-Hua, Liu Jianjun, Zeng Yi-Xin, Bei Jin-Xin
Abstract excerpt
To further identify novel susceptibility loci of nasopharyngeal carcinoma (NPC), we here extended our previous genome-wide association study (GWAS) by boosting statistical power with larger sample size and validating more SNPs in the ranking list based on the GWAS P-values. The discovery stage consisting of 463,250 SNPs in 1,583 cases and 2,979 controls of southern Chinese ancestry revealed 1,257 top SNPs to be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
