Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants of cell cycle pathway genes are associated with head and neck squamous cell carcinoma in the Chinese population.

Carcinogenesis - 12 Nov 2021

Chen Mo, Xu Wen-Mao, Wang Gui-Yang, Hou Ya-Xuan, Tian Ting-Ting, Li Yu-Qing, Qi Hong-Jiao, Zhou Meng, Kong Wei-Jia, Lu Mei-Xia

Abstract excerpt

Genetic alterations in the cell cycle pathway are common in head and neck squamous cell carcinoma (HNSCC). We identified four novel HNSCC susceptibility loci (CDKN1C rs452338, CDK4 rs2072052, E2F2 rs3820028 and E2F2 rs2075993) through a two-stage matched case-control study. There was a combined effect among the four single nucleotide polymorphisms (SNPs), as the number of risk genotypes increased, the risk of...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Cell Movement
Share to Genes, cdc
Share to Head and Neck Neoplasms
Share to Methyltransferases
Share to MicroRNAs
Share to Neoplasm Invasiveness
Share to Squamous Cell Carcinoma of Head and Neck

Source

Identifiers

PMID: 34643214
DOI: 10.1093/carcin/bgab094

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants of cell cycle pathway genes are associated with head and neck squamous cell carcinoma in the Chinese population.PMID 34643214Read ↗

Potentially functional polymorphisms in cell cycle genes and the survival of non-small cell lung cancer in a Chinese population.Semantic proximity Read ↗

The Nonsynonymous Polymorphisms Val276Met and Gly393Ser of E2F1 Gene are Strongly Associated with Lung, and Head and Neck Cancers.Semantic proximity Read ↗

Genetic variants of cell cycle pathway genes predict disease-free survival of hepatocellular carcinoma.Semantic proximity Read ↗

Combined effects of E2F1 and E2F2 polymorphisms on risk and early onset of squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

ATG12 expression quantitative trait loci associated with head and neck squamous cell carcinoma risk in a Chinese Han population.Semantic proximity Read ↗

Identification of Potential Biomarkers and Survival Analysis for Head and Neck Squamous Cell Carcinoma Using Bioinformatics Strategy: A Study Based on TCGA and GEO DatasetsSemantic proximity Read ↗

Mutational landscape of head and neck cancer and cervical cancer in Chinese and Western population.Semantic proximity Read ↗

Genetic variants associated with expression of TCF19 contribute to the risk of head and neck cancer in Chinese population.Semantic proximity Read ↗

Roles of E2F family members in the diagnosis and prognosis of head and neck squamous cell carcinomaSemantic proximity Read ↗

Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancySemantic proximity Read ↗

Interaction analysis between germline genetic variants and somatic mutations in head and neck cancer.Semantic proximity Read ↗

Identification of nsSNPs of transcription factor E2F1 predisposing individuals to lung cancer and head and neck cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.