Article
Integrative genomic analysis identified common regulatory networks underlying the correlation between coronary artery disease and plasma lipid levels.
BMC cardiovascular disorders - 23 Dec 2019
Chen Liuying, Yao Yinghao, Jin Chaolun, Wu Shen, Liu Qiang, Li Jingjing, Ma Yunlong, Xu Yizhou, Zhong Yigang
Abstract excerpt
BACKGROUND: Coronary artery disease (CAD) and plasma lipid levels are highly correlated, indicating the presence of common pathways between them. Nevertheless, the molecular pathways underlying the pathogenic comorbidities for both traits remain poorly studied. We sought to identify common pathways and key driver genes by performing a comprehensive integrative analysis based on multi-omic datasets. METHODS: By...
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