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Article

RCM: a novel association approach to search for coronary artery disease genetic related metabolites based on SNPs and metabolic network.

Genomics - 1 Nov 2012

Li Xu, Chen Lina, Zhang Liangcai, Li Wan, Jia Xu, Li Weiguo, Qu Xiaoli, Tai Jingxie, Feng Chenchen, Zhang Fan, He Weiming

Abstract excerpt

Integration of genetic and metabolic network holds promise for providing insight into human disease. Coronary artery disease (CAD) is strongly heritable, but the heritability of metabolic compounds has not been evaluated in human metabolic context. Here we performed a genetic-based computational approach within eight sub-cellular networks from Edinburgh Human Metabolic Network to identify significant genetic risk...

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Source

Identifiers

PMID: 22850356
DOI: 10.1016/j.ygeno.2012.07.013

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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