Article
Identification of Risk Pathways and Functional Modules for Coronary Artery Disease Based on Genome-wide SNP Data.
Genomics, proteomics & bioinformatics - 1 Dec 2016
Zhao Xiang, Luan Yi-Zhao, Zuo Xiaoyu, Chen Ye-Da, Qin Jiheng, Jin Lv, Tan Yiqing, Lin Meihua, Zhang Naizun, Liang Yan, Rao Shao-Qi
Abstract excerpt
Coronary artery disease (CAD) is a complex human disease, involving multiple genes and their nonlinear interactions, which often act in a modular fashion. Genome-wide single nucleotide polymorphism (SNP) profiling provides an effective technique to unravel these underlying genetic interplays or their functional involvements for CAD. This study aimed to identify the susceptible pathways and modules for CAD based...
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