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TIMP-2 Polymorphisms Define Subtypes of Hypertensive Intracerebral Hemorrhage with Distinct Perihematomal Edema Development Patterns.

Current neurovascular research - 1 Jan 2020

Chen Ru, Song Zhi, Deng Mingzhu, Zheng Wen, Liu Jia, Huang Lihua

Abstract excerpt

BACKGROUND: Perihematomal edema (PHE) is a major threat leading to poor functional outcomes after intracerebral hemorrhage (ICH). TIMP-2 is considered to participate in the formation of PHE after ICH by antagonizing the damaging effects of MMP-2. In the early study, the polymorphisms of TIMP-2 rs8179090 have shown to influence the expression of TIMP-2. OBJECTIVE: To prove that the severity of PHE was different in...

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PMID: 31870265
DOI: 10.2174/1567202617666191223145632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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