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Influence of COL1A2 gene variants on the incidence of hypertensive intracerebral hemorrhage in a Chinese population.

Genetics and molecular research : GMR - 22 Feb 2016

Tian D Z, Wei W, Dong Y J

Abstract excerpt

Type I collagen (transcribed by COL1A1 and COL1A2 genes) is important for maintaining vessel wall elasticity and is a critical part of the extracellular matrix. We conducted a case-control study to investigate the role of the COL1A2 rs42524 polymorphism in the development of hypertensive intracerebral hemorrhage. Between January 2012 and December 2014, a total of 227 patients with hypertensive intracerebral...

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PMID: 26910001
DOI: 10.4238/gmr.15017369

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