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Article

Polymorphisms in the Promoters of the MMP-2 and TIMP-2 Genes Are Associated with Spontaneous Deep Intracerebral Hemorrhage in the Taiwan Population.

PloS one - 1 Jan 2015

Chen Yi Chun, Ho Wei Min, Lee Yun Shien, Chen Huei Wen, Chen Chiung-Mei

Abstract excerpt

BACKGROUND: Spontaneous intracerebral hemorrhage (ICH) is a devastating stroke subtype. Matrix metalloproteinases (MMPs) function in the degradation of extracellular matrix and the activities of MMPs are modulated by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). This study aimed to discuss relationship of MMP-2 and TIMP-2 to spontaneous deep ICH (SDICH) susceptibility and hematoma...

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Share to Cerebral Hemorrhage
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Matrix Metalloproteinase 2

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Source

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Identifiers

PMID: 26551785
DOI: 10.1371/journal.pone.0142482
PMCID: PMC4638341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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