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Article

TT genotype of the MMP-9-1562C/T polymorphism may be a risk factor for thrombolytic therapy-induced hemorrhagic complications after acute ischemic stroke.

Pharmacotherapy - 1 Jul 2021

Dusanovic Pjevic Marija, Jekic Biljana, Beslac Bumbasirevic Ljiljana, Vojvodic Ljubica, Damnjanovic Tatjana, Grk Milka, Maksimovic Nela, Pesic Milica, Gulic Milica, Trickovic Jelena, Kacar Katarina

Abstract excerpt

INTRODUCTION: Levels of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) influence recombinant tissue plasminogen activator (rtPA) therapy response in patients with acute ischemic stroke (AIS). Serum levels of MMPs and TIMPs along with the expression of genes coding these proteins are related to the recovery and appearance of adverse effects (AE) after AIS. Consequently, it is important to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Matrix Metalloproteinase 9

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Share to Tissue Inhibitor of Metalloproteinase-2

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Source

Identifiers

PMID: 33942334
DOI: 10.1002/phar.2532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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